DIPHTHERIA ANTITOXIN.

Studies of Diphtheria Antitoxin in Rheumatic Fever

The importance of group A hemolytic streptococcal infections in the pathogenesis of rheumatic fever is widely recognized, but little is known of the mechanism by which the streptococcal infection gives rise to the disease. The concept that an antigen-antibody interaction may be involved in the origin of the pathologic processes has received increasing attention, and recent antibody studies (1, ...

Purification and Crystallization of Diphtheria Antitoxin

Purified preparations of diphtheria antitoxin have been obtained by digestion of the toxin-antitoxin complex with trypsin, followed by fractional precipitation with ammonium sulfate. The various fractions obtained in this way are all 90 per cent or more precipitated by diphtheria toxin but combine with different quantities of the toxin. The fraction precipitated between 0.33 and 0.5 saturated a...

Xlvii. the Heat Inactivation of Diphtheria Antitoxin

Naturally Developed Diphtheria Antitoxin Titre of a Random Indian Population

The distribution of diphtheria antitoxin in pepsin-digested horse antiserum.